منابع مشابه
Restenosis and drug-eluting stents.
The implantation of intracoronary stents for the treatment of coronary atherosclerotic disease is one of the most common percutaneous procedures. While the procedure brings long-term benefit for a large percentage of patients, a significant number of patients experience in-stent restenosis (ISR). ISR may be caused by a number of biological and procedural factors, including lesion characteristic...
متن کاملDrug-eluting stents: the end of restenosis?
One of the major advancements in interventional cardiology has been the introduction of drug-eluting stents (DES). By incorporating anti-proliferative agents onto the surface of the stent, neointimal hyperplasia occurring within the stent, which is the main cause of in-stent restenosis (ISR), is markedly reduced. Stents coated with agents, like sirolimus or paclitaxel, when compared to bare met...
متن کاملIntracoronary brachytherapy for in-stent restenosis of drug-eluting stents
PURPOSE Given the limited salvage options for in-stent restenosis (ISR) of drug-eluting stents (DES), our high-volume cardiac catheterization laboratory has been performing intracoronary brachytherapy (ICBT) in patients with recurrent ISR of DES. This study analyzes their baseline characteristics and assesses the safety/toxicity of ICBT in this high-risk population. METHODS AND MATERIALS A re...
متن کاملMolecular basis of restenosis and drug-eluting stents.
Dr Forrester’s prediction that resolution of restenosis would require the translational merging of molecular mechanisms of proliferation with local scaffolding and drugdelivery devices appears to have been remarkably prescient. The application of drug-eluting stent (DES) technology to improve clinical outcomes after percutaneous coronary intervention (PCI) represents one of the greatest success...
متن کاملDrug Eluting Stents – Do They Address the Problem of Restenosis?
Percutaneous coronary intervention (PCI) has revolutionised the treatment of coronary artery disease, which remains one of the major causes of mortality in developed nations throughout the world. It is used to treat patients with both stable angina and acute coronary syndromes, and is also the treatment of choice in acute STelevation myocardial infarction. PCI is popular with patients when comp...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Interventions
سال: 2019
ISSN: 1941-7640,1941-7632
DOI: 10.1161/circinterventions.118.007023